A Caregiver’s Guide: Cleaning Out a Loved One’s Medications

Author: Phil Baker, PharmD

If you’re a caregiver facing a cabinet, drawer, or shoebox full of someone else’s medications, it can feel surprisingly overwhelming. Sometimes, the chore of cleaning out medications can be unexpected. It may come when a loved one transitions to hospice, a spouse’s treatment changes, or a relative passes away. 

You may have dozens of meds and no obvious instructions for what to do with them. 

Let me walk you through it the way I’d walk a family member through it at the pharmacy: calmly, step by step, and without guilt about whatever you decide. 

As a pharmacist with more than 20 years of experience, I’ve helped a number of caregivers through this very task. In short, the goal is simply to keep medications out of the wrong hands, safely dispose of meds that need it, and – if you’d like – let valuable medication help someone instead of going in the trash.


1. Sort unused medications into two piles.

If you’re faced with a number of unused medications, start with a flat surface and a little time. Sort them into two piles:

Safe Disposal

This pile will be larger. It should include any medications that:

  • are expired;
  • have been opened (including loose pills, even those in pharmacy-issued brown bottles);
  • are considered controlled substances;
  • require refrigeration or other special handling.
Donation

This smaller pile is ideal for medications that are:

  • unopened (sealed in the manufacturer’s packaging – including blister packs);
  • unexpired (ideally with at least six months before the expiration date);
  • non-controlled substances;
  • stored at room temperature.

Prescriptions in the donation pile may be eligible for reclamation by a licensed Medication Rescue program to help another patient in need. This is especially true of high-cost medications, like those for cancer. 

As you sort, you don’t have to identify every pill or know every rule. A pharmacist or donation program will help you sort it. And there’s no deadline. Do this at whatever pace feels manageable.

 

2. Take care of the disposal pile safely.

A few options are available for safe medication disposal. These include:

  1. Bring them to a pharmacy dropbox. Click here to find dropbox locations near you. Medications surrendered to these dropboxes will be handled properly in accordance with standard medication disposal practices employed by pharmacies. 
    • In addition to those at pharmacies, many law enforcement agencies have 24/7 secure dropboxes for controlled substances. Contact your local law enforcement agency to find out if a disposal location is available near you. 
  2. Surrender them at a take-back location on the next DEA Take-Back Day. Take-back days typically happen twice per year. When they occur, thousands of locations across the country participate, making it likely you’ll find a take-back spot near you. Click here for more information.
  3. Purchase a mail-order disposal kit. Companies like Deterra offer mail-order kits to safely and appropriately dispose of medications that are ineligible for donation (like controlled substances and opened or expired prescriptions). The caveat with this is that it comes at a cost for caregivers, while options like pharmacy dropboxes or DEA Take-Back events are free. Still, it’s a valid option, especially if the caregiver has no means of properly securing or storing these medications until a dropbox or take-back event option is available.

Although you may find suggestions online for home disposal or advice to flush certain medications, it’s important to avoid home disposal methods if at all possible. Generally, home disposal works to make medications unusable and to prevent something like a controlled substance from being abused by someone else. But home disposal does not effectively break down pharmaceuticals, even those mixed with something like kitty litter. When medications are disposed of improperly, they often wind up in places they shouldn’t, like our water supplies.

3. Handle the donation pile.

It’s worth pursuing donation for unexpired, sealed medications (especially the valuable ones). It can be a literal lifesaver for another patient who may otherwise go without the same necessary prescription. 

Start by identifying a Medication Rescue organization that can process your donation(s). A licensed organization will check each medication, have a pharmacist verify it, and actively work to direct it to a patient in need. 

When choosing a Medication Rescue partner, look for one that meets the following criteria:

  • The organization operates as a nonprofit. This ensures the organization’s focus is on the patients first, regardless of any financial considerations.
  • The organization employs a licensed pharmacist…or several of them. Medication Rescue can and should operate with the same safety protocols and precision as any other pharmacy. 
  • Eligible medication donations should ship at no cost to donors. 
  • The organization should have an in-depth knowledge of the laws surrounding medication donation and reuse. This includes the laws governing donated medications, those that may apply to patients who access donated medication as a form of prescription assistance, those that apply to you as a donor, and those that apply to their organization. Ask your questions – they should have answers!
  • Donors should have a clear understanding of where medications go. Some organizations are local or state-based, meaning medications are likely to be shared with patients in those geographic areas. Others handle both the donation and dispensing sides, while some may direct donations to third-party clinics. Ideally, you should know how patients can get medication from any organization willing to accept your donation.

Common Caregiver Concerns About Cleaning Out Unused Medications


“There are so many medications — is going through them a huge project?” 

Not necessarily. When going through unused medications, most bottles can be sorted quickly into the disposal pile once you spot that they’re opened or expired. The donation pile is often small – just the few sealed, expensive ones – and those are the ones worth the extra step.

“Is it legal for me to donate someone else’s medication?” 

Passing prescription medication from one individual to another is illegal. But donating eligible medication through a licensed program is acceptable in most states, and a trustworthy organization should know the laws that apply to their work, to donors, and to any recipients. Laws vary by state, so make sure your Medication Rescue partner is well-versed in them.

“Is donated medication safe for patients who get it later?” 

Yes. That’s one good reason to choose a Medication Rescue partner with a licensed pharmacist on staff. A pharmacist should inspect every donation and add only sealed, unexpired, properly stored medication to inventory to be shared with patients in need.

“What about the patient’s privacy?” 

Good instinct.

  • Among medications set aside for disposal, remove the labels, if possible. If not, scratch out names and personal details prior to bringing them to a pharmacy dropbox or turning them in at a DEA Take-Back event.
  • Among medications eligible for donation, labels actually need to stay intact, at least for a little while. The expiration dates, lot numbers, and other label information are critical pieces of verifying donated medications prior to adding them to inventory. But don’t worry – your Medication Rescue partner will safely and completely remove and dispose of these labels prior to making the prescription available to a patient in need. If you have any questions about that, contact the organization. They should be able to quickly and confidently address your concerns.

“I can’t face this right now.” 

You don’t have to do it immediately. Secure the medications, especially any controlled substances, and come back to it when you’re ready.

 

A Note for Caregivers

Cleaning out a loved one’s medications is rarely just a chore. It often carries something heavier, especially after a loss or a big transition. 

Be patient with yourself. Whatever you choose to do with these medications is okay. If donating the valuable ones gives you a sense that something good came of this, that’s a lovely thing. And if you simply want it all handled and gone, that’s fine too. The right way to do this is the way that works best for you.

 

Where to Donate Eligible Medication

There are programs built specifically for this – the process is called Medication Rescue. Whether you’ve got high-cost medications like oral anticancer drugs, several cycles of specialty therapies, or even a stash of anti-coagulants, it can be lifesaving to a patient who may otherwise go without. 

Here are a few options that may work for you:

  • A National Nonprofit – RemediChain legally and safely rescues donation-eligible medication from both individuals and systems anywhere in the United States. The organization also maintains an inventory of verified donated medications to provide prescription assistance to eligible patients across the country. Click here to access the medication donation form, which automatically filters for donation eligibility. 
  • State-Based Organizations – If you live in Iowa or Nebraska, SafeNetRx is a local repository serving the needs of residents in those states. Click here for more information.
  • Community Clinics – Occasionally, local clinics may have medication repositories. This is highly specific to the laws in your state and the services available in your area.

Have Questions or Concerns?

Click here to contact us. Our staff is well-versed in state-level Medication Rescue laws, as well as what prescriptions may be eligible for donation versus disposal.  

This article is for general education and isn’t medical or legal advice. Medication donation eligibility and disposal rules vary by state and change over time; a licensed pharmacist or the donation program can confirm what applies to a specific medication.